Impact of scaling up dolutegravir on antiretroviral resistance in South Africa: A modeling study.

<h4>Background</h4>Rising resistance of HIV-1 to non-nucleoside reverse transcriptase inhibitors (NNRTIs) threatens the success of the global scale-up of antiretroviral therapy (ART). The switch to WHO-recommended dolutegravir (DTG)-based regimens could reduce this threat due to DTG'...

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Bibliographic Details
Main Authors: Anthony Hauser, Katharina Kusejko, Leigh F Johnson, Huldrych F Günthard, Julien Riou, Gilles Wandeler, Matthias Egger, Roger D Kouyos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-12-01
Series:PLoS Medicine
Online Access:https://doi.org/10.1371/journal.pmed.1003397