miR-125b regulates chemotaxis and survival of bone marrow derived granulocytes in vitro and in vivo.

miR-125b regulates chemotaxis and survival of bone marrow derived granulocytes in vitro and in vivo.

The evolutionary conserved miR-125b is highly expressed in hematopoietic stem cells (HSC) enhancing self-renewal and survival. Accordingly, over-expression of miR-125b in HSC may induce myeloproliferative neoplasms and leukemia with long latency. During hematopoietic cell maturation miR-125b express...

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Bibliographic Details
Main Authors: Chun-Wei Lee, Caroline Schoenherr, Karin Battmer, Arnold Ganser, Denise Hilfiker-Kleiner, Sascha David, Matthias Eder, Michaela Scherr
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6171867?pdf=render

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http://europepmc.org/articles/PMC6171867?pdf=render

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