Psoriasis flare-ups following sorafenib therapy: A rare case

Sorafenib is a multikinase inhibitor that blocks tumor cell proliferation and angiogenesis. While adverse skin reactions occur in 90% of patients treated with angiogenesis inhibitors, only a few cases of psoriasiform eruption associated with sorafenib therapy have been reported. We report a rare cas...

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Main Authors:	Ming-Chun Hsu, Chih-Chiang Chen
Format:	Article
Language:	English
Published:	Wolters Kluwer Medknow Publications 2016-09-01
Series:	Dermatologica Sinica
Subjects:	kinase inhibitor psoriasiform eruption psoriasis sorafenib
Online Access:	http://www.sciencedirect.com/science/article/pii/S1027811716000057

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spelling	doaj-5a40e4db1a664494909f0ec0be6cafa42020-11-24T21:34:28ZengWolters Kluwer Medknow PublicationsDermatologica Sinica1027-81172016-09-0134314815010.1016/j.dsi.2016.01.004Psoriasis flare-ups following sorafenib therapy: A rare caseMing-Chun Hsu0Chih-Chiang Chen1Department of Dermatology, Taipei Veterans General Hospital and National Yang-Ming University, Taipei, TaiwanDepartment of Dermatology, Taipei Veterans General Hospital and National Yang-Ming University, Taipei, TaiwanSorafenib is a multikinase inhibitor that blocks tumor cell proliferation and angiogenesis. While adverse skin reactions occur in 90% of patients treated with angiogenesis inhibitors, only a few cases of psoriasiform eruption associated with sorafenib therapy have been reported. We report a rare case of sorafenib-related psoriasis that responded well to topical treatment and narrow-band UV-B phototherapy after discontinuation of sorafenib.http://www.sciencedirect.com/science/article/pii/S1027811716000057kinase inhibitorpsoriasiform eruptionpsoriasissorafenib
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Ming-Chun Hsu Chih-Chiang Chen
spellingShingle	Ming-Chun Hsu Chih-Chiang Chen Psoriasis flare-ups following sorafenib therapy: A rare case Dermatologica Sinica kinase inhibitor psoriasiform eruption psoriasis sorafenib
author_facet	Ming-Chun Hsu Chih-Chiang Chen
author_sort	Ming-Chun Hsu
title	Psoriasis flare-ups following sorafenib therapy: A rare case
title_short	Psoriasis flare-ups following sorafenib therapy: A rare case
title_full	Psoriasis flare-ups following sorafenib therapy: A rare case
title_fullStr	Psoriasis flare-ups following sorafenib therapy: A rare case
title_full_unstemmed	Psoriasis flare-ups following sorafenib therapy: A rare case
title_sort	psoriasis flare-ups following sorafenib therapy: a rare case
publisher	Wolters Kluwer Medknow Publications
series	Dermatologica Sinica
issn	1027-8117
publishDate	2016-09-01
description	Sorafenib is a multikinase inhibitor that blocks tumor cell proliferation and angiogenesis. While adverse skin reactions occur in 90% of patients treated with angiogenesis inhibitors, only a few cases of psoriasiform eruption associated with sorafenib therapy have been reported. We report a rare case of sorafenib-related psoriasis that responded well to topical treatment and narrow-band UV-B phototherapy after discontinuation of sorafenib.
topic	kinase inhibitor psoriasiform eruption psoriasis sorafenib
url	http://www.sciencedirect.com/science/article/pii/S1027811716000057
work_keys_str_mv	AT mingchunhsu psoriasisflareupsfollowingsorafenibtherapyararecase AT chihchiangchen psoriasisflareupsfollowingsorafenibtherapyararecase
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Psoriasis flare-ups following sorafenib therapy: A rare case

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