Neuropilin-1highCD4+CD25+ Regulatory T Cells Exhibit Primary Negative Immunoregulation in Sepsis

Neuropilin-1highCD4+CD25+ Regulatory T Cells Exhibit Primary Negative Immunoregulation in Sepsis

Regulatory T cells (Tregs) appear to be involved in sepsis-induced immune dysfunction; neuropilin-1 (Nrp-1) was identified as a surface marker for CD4+CD25+Tregs. In the current study, we investigated the negative immunoregulation of Nrp-1highCD4+CD25+Tregs and the potential therapeutic value of Nrp...

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Bibliographic Details
Main Authors:	Yu-Lei Gao, Yan-Fen Chai, An-Long Qi, Ying Yao, Yan-Cun Liu, Ning Dong, Li-Jun Wang, Yong-Ming Yao
Format:	Article
Language:	English
Published:	Hindawi Limited 2016-01-01
Series:	Mediators of Inflammation
Online Access:	http://dx.doi.org/10.1155/2016/7132158

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