Antitumor Effect of Pyrogallol via miR-134 Mediated S Phase Arrest and Inhibition of PI3K/AKT/Skp2/cMyc Signaling in Hepatocellular Carcinoma

Antitumor Effect of Pyrogallol via miR-134 Mediated S Phase Arrest and Inhibition of PI3K/AKT/Skp2/cMyc Signaling in Hepatocellular Carcinoma

Though Pyrogallol, one of the natural polyphenols, was known to have anti-inflammatory and antitumor effects in breast and colon cancers, the underlying antitumor mechanisms of Pyrogallol, still remain unclear so far. Here, the antitumor mechanisms of Pyrogallol were elucidated in Hep3B and Huh7 hep...

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Bibliographic Details
Main Authors: Hyojin Ahn, Eunji Im, Dae Young Lee, Hyo-Jung Lee, Ji Hoon Jung, Sung-Hoon Kim
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:International Journal of Molecular Sciences
Subjects:
Pyrogallol
S-phase arrest
c-Myc
Skp2
miR-134
Online Access:https://www.mdpi.com/1422-0067/20/16/3985

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