Controlled fluorescence quenching by antibody-conjugated graphene oxide to measure tau protein

Controlled fluorescence quenching by antibody-conjugated graphene oxide to measure tau protein

We report an ultrasensitive immunoassay for tau protein—a key marker of Alzheimer's disease. This sensing platform relies on graphene oxide (GO) surfaces conjugated with anti-human tau antibody to provide quantitative binding sites for the tau protein. The GO quenches standard fluorescein isoth...

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Bibliographic Details
Main Authors: Ao Huang, Luning Zhang, Weiwei Li, Zeyu Ma, Shi Shuo, Tianming Yao
Format: Article
Language:English
Published: The Royal Society 2018-01-01
Series:Royal Society Open Science
Subjects:
tau protein
alzheimer's disease
biosensor
graphene oxide
immunoassay
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.171808

Internet

https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.171808

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