Simultaneous recordings of action potentials and calcium transients from human induced pluripotent stem cell derived cardiomyocytes

Simultaneous recordings of action potentials and calcium transients from human induced pluripotent stem cell derived cardiomyocytes

Human induced pluripotent stem cell derived cardiomyocytes (hiPSC-CMs) offer a unique in vitro platform to study cardiac diseases, as they recapitulate many disease phenotypes. The membrane potential (Vm) and intracellular calcium (Ca2+) transient (CaT) are usually investigated separately, because i...

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Bibliographic Details
Main Authors: Chandra Prajapati, Risto-Pekka Pölönen, Katriina Aalto-Setälä
Format: Article
Language:English
Published: The Company of Biologists 2018-07-01
Series:Biology Open
Subjects:
hiPSC-CMs
Membrane potential
Calcium transient
Delayed after depolarization
Early after depolarization
Online Access:http://bio.biologists.org/content/7/7/bio035030

Internet

http://bio.biologists.org/content/7/7/bio035030

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