Psoralen Induces Developmental Toxicity in Zebrafish Embryos/Larvae Through Oxidative Stress, Apoptosis, and Energy Metabolism Disorder

Psoralen Induces Developmental Toxicity in Zebrafish Embryos/Larvae Through Oxidative Stress, Apoptosis, and Energy Metabolism Disorder

Psoralen toxicity is an issue of wide concern. However, an assay for psoralen-induced developmental toxicity has not been reported to date. Moreover, the underlying mechanism of psoralen-induced developmental toxicity is unclear. Therefore, this study attempted to develop a psoralen-induced developm...

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Bibliographic Details
Main Authors: Qing Xia, Lingying Wei, Yun Zhang, Haotian Kong, Yongping Shi, Xue Wang, Xiqiang Chen, Liwen Han, Kechun Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Pharmacology
Subjects:
psoralen
zebrafish
developmental toxicity
oxidative stress
apoptosis
energy metabolism disorder
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.01457/full

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