Use of a Continuous Glucose Monitor for Preoperative Monitoring and Treatment of Hypoglycemia in a Case of Pancreatic Neuroendocrine Tumor

Use of a Continuous Glucose Monitor for Preoperative Monitoring and Treatment of Hypoglycemia in a Case of Pancreatic Neuroendocrine Tumor

ABSTRACT: Objective: Pancreatic neuroendocrine tumors secreting proinsulin and insulin could lead to life-threatening hypoglycemia. We aim to show this can be avoided by utilizing continuous glucose monitoring. Methods: We describe a case of a 55-year-old female with hypoglycemia unawareness and se...

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Main Authors: Ryan C. Lyerla, MD, Arrsh Bajaj, MS, Rupendra T. Shrestha, MD
Format: Article
Language:English
Published: Elsevier 2019-07-01
Series:AACE Clinical Case Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2376060520300924
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spelling doaj-5a027ee962ad4a39b2056292d1f5e59a2021-04-30T07:23:30ZengElsevierAACE Clinical Case Reports2376-06052019-07-0154e255e258Use of a Continuous Glucose Monitor for Preoperative Monitoring and Treatment of Hypoglycemia in a Case of Pancreatic Neuroendocrine TumorRyan C. Lyerla, MD0Arrsh Bajaj, MS1Rupendra T. Shrestha, MD2Address correspondence to Dr. Ryan C. Lyerla, University of Minnesota, Division of Endocrinology, Diabetes and Metabolism, 420 Delaware Street Southeast, MMC 101, Minneapolis, MN 55455.; From the 1Division of Endocrinology, Diabetes and Metabolism, University of Minnesota, MinneapolisKasturba Medical College, Manipal, Kamataka, India.From the 1Division of Endocrinology, Diabetes and Metabolism, University of Minnesota, MinneapolisABSTRACT: Objective: Pancreatic neuroendocrine tumors secreting proinsulin and insulin could lead to life-threatening hypoglycemia. We aim to show this can be avoided by utilizing continuous glucose monitoring. Methods: We describe a case of a 55-year-old female with hypoglycemia unawareness and seizures diagnosed with proinsulinoma. She utilized an intermittently scanned continuous glucose monitor (isCGM) to monitor hypoglycemia preoperatively. Results: The patient underwent biochemical and radiographic evaluation to confirm the diagnosis of proinsulinoma. Utilizing isCGM to monitor blood glucose, she was able to prevent hypoglycemia-related seizures prior to definitive surgery. Conclusion: In the time leading up to a definitive surgery, patients with proinsulinomas are at risk of hypoglycemic events leading to falls, seizures, and even death. isCGMs can be utilized for preoperative monitoring and treatment of hypoglycemia in these patients.http://www.sciencedirect.com/science/article/pii/S2376060520300924
collection DOAJ
language English
format Article
sources DOAJ
author Ryan C. Lyerla, MD
Arrsh Bajaj, MS
Rupendra T. Shrestha, MD
spellingShingle Ryan C. Lyerla, MD
Arrsh Bajaj, MS
Rupendra T. Shrestha, MD
Use of a Continuous Glucose Monitor for Preoperative Monitoring and Treatment of Hypoglycemia in a Case of Pancreatic Neuroendocrine Tumor
AACE Clinical Case Reports
author_facet Ryan C. Lyerla, MD
Arrsh Bajaj, MS
Rupendra T. Shrestha, MD
author_sort Ryan C. Lyerla, MD
title Use of a Continuous Glucose Monitor for Preoperative Monitoring and Treatment of Hypoglycemia in a Case of Pancreatic Neuroendocrine Tumor
title_short Use of a Continuous Glucose Monitor for Preoperative Monitoring and Treatment of Hypoglycemia in a Case of Pancreatic Neuroendocrine Tumor
title_full Use of a Continuous Glucose Monitor for Preoperative Monitoring and Treatment of Hypoglycemia in a Case of Pancreatic Neuroendocrine Tumor
title_fullStr Use of a Continuous Glucose Monitor for Preoperative Monitoring and Treatment of Hypoglycemia in a Case of Pancreatic Neuroendocrine Tumor
title_full_unstemmed Use of a Continuous Glucose Monitor for Preoperative Monitoring and Treatment of Hypoglycemia in a Case of Pancreatic Neuroendocrine Tumor
title_sort use of a continuous glucose monitor for preoperative monitoring and treatment of hypoglycemia in a case of pancreatic neuroendocrine tumor
publisher Elsevier
series AACE Clinical Case Reports
issn 2376-0605
publishDate 2019-07-01
description ABSTRACT: Objective: Pancreatic neuroendocrine tumors secreting proinsulin and insulin could lead to life-threatening hypoglycemia. We aim to show this can be avoided by utilizing continuous glucose monitoring. Methods: We describe a case of a 55-year-old female with hypoglycemia unawareness and seizures diagnosed with proinsulinoma. She utilized an intermittently scanned continuous glucose monitor (isCGM) to monitor hypoglycemia preoperatively. Results: The patient underwent biochemical and radiographic evaluation to confirm the diagnosis of proinsulinoma. Utilizing isCGM to monitor blood glucose, she was able to prevent hypoglycemia-related seizures prior to definitive surgery. Conclusion: In the time leading up to a definitive surgery, patients with proinsulinomas are at risk of hypoglycemic events leading to falls, seizures, and even death. isCGMs can be utilized for preoperative monitoring and treatment of hypoglycemia in these patients.
url http://www.sciencedirect.com/science/article/pii/S2376060520300924
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