Computation-based virtual screening for designing novel antimalarial drugs by targeting falcipain-III: A structure-based drug designing approach

<b>Background & objectives</b>: Cysteine proteases (falcipains), a papain-family of enzymes of Plasmodium falciparum, are responsible for haemoglobin degradation and thus necessary for its survival during asexual life cycle phase inside the human red blood cells while remaining non-f...

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Bibliographic Details
Main Authors: Rajesh Kumar Kesharwani, Durg Vijay Singh, Krishna Misra
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2013-04-01
Series:Journal of Vector Borne Diseases
Subjects:
Online Access:http://www.mrcindia.org/journal/issues/502093.pdf