Exosomal-mediated transfer of APCDD1L-AS1 induces 5-fluorouracil resistance in oral squamous cell carcinoma via miR-1224-5p/nuclear receptor binding SET domain protein 2 (NSD2) axis

Exosomal-mediated transfer of APCDD1L-AS1 induces 5-fluorouracil resistance in oral squamous cell carcinoma via miR-1224-5p/nuclear receptor binding SET domain protein 2 (NSD2) axis

Oral squamous cell carcinoma (OSCC) poses a threat to public health worldwide. LncRNA APCDD1L-AS1 has been reported to participate in tumorigenesis and development of acquired chemoresistance. However, the role of APCDD1L-AS1 in 5-fluorouracil (5-FU) resistance regulation within OSCC is still obscur...

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Bibliographic Details
Main Authors: Shen Li, Zhiyan Shi, Suwei Fu, Qingfu Li, Bei Li, Lixiao Sang, Donghong Wu
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Bioengineered
Subjects:
apcdd1l-as1
5-fluorouracil
mir-1224-5p
nsd2
oral squamous cell carcinoma
Online Access:http://dx.doi.org/10.1080/21655979.2021.1979442

Internet

http://dx.doi.org/10.1080/21655979.2021.1979442

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