A parallel implementation of the Wuchty algorithm with additional experimental filters to more thoroughly explore RNA conformational space.

A parallel implementation of the Wuchty algorithm with additional experimental filters to more thoroughly explore RNA conformational space.

We present new modifications to the Wuchty algorithm in order to better define and explore possible conformations for an RNA sequence. The new features, including parallelization, energy-independent lonely pair constraints, context-dependent chemical probing constraints, helix filters, and optional...

Full description

Bibliographic Details
Main Authors: Jonathan W Stone, Samuel Bleckley, Sean Lavelle, Susan J Schroeder
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0117217

Similar Items

Similar Items