Stability of the PHF10 subunit of PBAF signature module is regulated by phosphorylation: role of β-TrCP

Stability of the PHF10 subunit of PBAF signature module is regulated by phosphorylation: role of β-TrCP

Abstract The PBAF chromatin-remodeling complexes are multi-protein machines, regulating expression of genes involved in proliferation and differentiation. PHF10 is a subunit of the PBAF essential for its association with chromatin. Mammalian PHF10 is expressed as four ubiquitous isoforms, which are...

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Bibliographic Details
Main Authors: Victor V. Tatarskiy, Yuriy P. Simonov, Dmitrii S. Shcherbinin, Alexander V. Brechalov, Sofia G. Georgieva, Nataliya V. Soshnikova
Format: Article
Language:English
Published: Nature Publishing Group 2017-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-05944-3

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