Bovine Milk Lactoferrin Selectively Kills Highly Metastatic Prostate Cancer PC-3 and Osteosarcoma MG-63 Cells In Vitro

Bovine Milk Lactoferrin Selectively Kills Highly Metastatic Prostate Cancer PC-3 and Osteosarcoma MG-63 Cells In Vitro

Prostate cancer and osteosarcoma are the second most common type of cancer affecting men and the fifth most common malignancy among adolescents, respectively. The use of non-toxic natural or natural-derived products has been one of the current strategies for cancer therapy, owing to the reduced risk...

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Bibliographic Details
Main Authors: Joana P. Guedes, Cátia S. Pereira, Lígia R. Rodrigues, Manuela Côrte-Real
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Oncology
Subjects:
highly metastatic cancer cells
V-ATPase
bovine lactoferrin
cancer therapy
intracellular pH
lysosomal dysfunction
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2018.00200/full

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