Protein Palmitoylation and Pathogenesis in Apicomplexan Parasites

Protein Palmitoylation and Pathogenesis in Apicomplexan Parasites

Apicomplexan parasites comprise a broad variety of protozoan parasites, including Toxoplasma gondii, Plasmodium, Eimeria, and Cryptosporidium species. Being intracellular parasites, the success in establishing pathogenesis relies in their ability to infect a host-cell and replicate within it. Protei...

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Main Authors: Maria Martha Corvi, Andres Mariano Alonso, Marina Cecilia Caballero
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Journal of Biomedicine and Biotechnology
Online Access:http://dx.doi.org/10.1155/2012/483969
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spelling doaj-59a62da018e24251a93c0da0e6272c382020-11-25T01:35:52ZengHindawi LimitedJournal of Biomedicine and Biotechnology1110-72431110-72512012-01-01201210.1155/2012/483969483969Protein Palmitoylation and Pathogenesis in Apicomplexan ParasitesMaria Martha Corvi0Andres Mariano Alonso1Marina Cecilia Caballero2Laboratorio de Parasitologia Molecular, Instituto Tecnológico de Chascomús (IIBINTECH), CONICET-Universidad Nacional de General San Martín, Intendente Marino Km 8,2, P.O. Box 164, Chascomús, B7130IWA Buenos Aires, ArgentinaLaboratorio de Parasitologia Molecular, Instituto Tecnológico de Chascomús (IIBINTECH), CONICET-Universidad Nacional de General San Martín, Intendente Marino Km 8,2, P.O. Box 164, Chascomús, B7130IWA Buenos Aires, ArgentinaLaboratorio de Parasitologia Molecular, Instituto Tecnológico de Chascomús (IIBINTECH), CONICET-Universidad Nacional de General San Martín, Intendente Marino Km 8,2, P.O. Box 164, Chascomús, B7130IWA Buenos Aires, ArgentinaApicomplexan parasites comprise a broad variety of protozoan parasites, including Toxoplasma gondii, Plasmodium, Eimeria, and Cryptosporidium species. Being intracellular parasites, the success in establishing pathogenesis relies in their ability to infect a host-cell and replicate within it. Protein palmitoylation is known to affect many aspects of cell biology. Furthermore, palmitoylation has recently been shown to affect important processes in T. gondii such as replication, invasion, and gliding. Thus, this paper focuses on the importance of protein palmitoylation in the pathogenesis of apicomplexan parasites.http://dx.doi.org/10.1155/2012/483969
collection DOAJ
language English
format Article
sources DOAJ
author Maria Martha Corvi
Andres Mariano Alonso
Marina Cecilia Caballero
spellingShingle Maria Martha Corvi
Andres Mariano Alonso
Marina Cecilia Caballero
Protein Palmitoylation and Pathogenesis in Apicomplexan Parasites
Journal of Biomedicine and Biotechnology
author_facet Maria Martha Corvi
Andres Mariano Alonso
Marina Cecilia Caballero
author_sort Maria Martha Corvi
title Protein Palmitoylation and Pathogenesis in Apicomplexan Parasites
title_short Protein Palmitoylation and Pathogenesis in Apicomplexan Parasites
title_full Protein Palmitoylation and Pathogenesis in Apicomplexan Parasites
title_fullStr Protein Palmitoylation and Pathogenesis in Apicomplexan Parasites
title_full_unstemmed Protein Palmitoylation and Pathogenesis in Apicomplexan Parasites
title_sort protein palmitoylation and pathogenesis in apicomplexan parasites
publisher Hindawi Limited
series Journal of Biomedicine and Biotechnology
issn 1110-7243
1110-7251
publishDate 2012-01-01
description Apicomplexan parasites comprise a broad variety of protozoan parasites, including Toxoplasma gondii, Plasmodium, Eimeria, and Cryptosporidium species. Being intracellular parasites, the success in establishing pathogenesis relies in their ability to infect a host-cell and replicate within it. Protein palmitoylation is known to affect many aspects of cell biology. Furthermore, palmitoylation has recently been shown to affect important processes in T. gondii such as replication, invasion, and gliding. Thus, this paper focuses on the importance of protein palmitoylation in the pathogenesis of apicomplexan parasites.
url http://dx.doi.org/10.1155/2012/483969
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