Association between estrogen receptor gene polymorphisms and the development and progression of hepatocellular carcinoma
The development and progression of hepatocellular carcinoma (HCC) is associated with estrogen, which exerts its physiological effect by binding to estrogen receptor (ER). The function of ER is regulated by related genes, while the expression and function of these genes are affected by gene polymorph...
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| Format: | Article |
| Language: | zho |
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Editorial Department of Journal of Clinical Hepatology
2018-02-01
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| Series: | Linchuang Gandanbing Zazhi |
| Online Access: | http://www.lcgdbzz.org/qk_content.asp?id=8782 |
| Summary: | The development and progression of hepatocellular carcinoma (HCC) is associated with estrogen, which exerts its physiological effect by binding to estrogen receptor (ER). The function of ER is regulated by related genes, while the expression and function of these genes are affected by gene polymorphisms, and the genetic susceptibility to tumors is due to the combined effect of different genes and polymorphisms. Therefore, it is believed that ER gene polymorphisms may affect the development, progression, and prognosis of HCC. This article reviews the research advances in ER gene polymorphisms in recent years. |
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| ISSN: | 1001-5256 1001-5256 |