In vivo and in vitro effect of imipramine and fluoxetine on Na+,K+-ATPase activity in synaptic plasma membranes from the cerebral cortex of rats

In vivo and in vitro effect of imipramine and fluoxetine on Na+,K+-ATPase activity in synaptic plasma membranes from the cerebral cortex of rats

The effects of in vivo chronic treatment and in vitro addition of imipramine, a tricyclic antidepressant, or fluoxetine, a selective serotonin reuptake inhibitor, on the cortical membrane-bound Na+,K+-ATPase activity were studied. Adult Wistar rats received daily intraperitoneal injections of 10 mg/...

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Bibliographic Details
Main Authors: L.M. Zanatta, F.C. Nascimento, S.V.T. Barros, G.R.R.S. Silva, A.I. Zugno, C.A. Netto, A.T.S. Wyse
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2001-10-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
imipramine
fluoxetine
Na+,K+-ATPase
cerebral cortex
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001001000005

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001001000005

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