An agent-based model to investigate microbial initiation of Alzheimer’s via the olfactory system

An agent-based model to investigate microbial initiation of Alzheimer’s via the olfactory system

Abstract Background Alzheimer’s disease (AD) is a degenerative brain disease. A novel agent-based modelling framework was developed in NetLogo 3D to provide fundamental insights into the potential mechanisms by which a microbe (eg. Chlamydia pneumoniae) may play a role in late-onset AD. The objectiv...

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Bibliographic Details
Main Authors: Shalini Sundar, Carly Battistoni, Ryan McNulty, Fernando Morales, Jonathan Gorky, Henry Foley, Prasad Dhurjati
Format: Article
Language:English
Published: BMC 2020-04-01
Series:Theoretical Biology and Medical Modelling
Subjects:
Agent-based model
Biological modelling framework
Alzheimer’s disease
Olfactory system
NetLogo3-D
Microbiome
Online Access:http://link.springer.com/article/10.1186/s12976-020-00123-w

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