Noise Power Properties of Magnetic Nanoparticles as Measured in Thermal Noise Magnetometry
Magnetic nanoparticles have proven to be extremely useful in a broad range of biomedical applications. To ensure optimal efficiency, a precise characterization of these particles is required. Thermal Noise Magnetrometry (TNM) is a recently developed characterization technique that has already been v...
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doaj-598294c9a9e54059921a248caf1cbec02021-08-17T23:00:49ZengIEEEIEEE Access2169-35362021-01-01911150511151710.1109/ACCESS.2021.31023809505633Noise Power Properties of Magnetic Nanoparticles as Measured in Thermal Noise MagnetometryKatrijn Everaert0https://orcid.org/0000-0002-0013-0150Maik Liebl1Dirk Gutkelch2James Wells3https://orcid.org/0000-0002-4218-128XBartel Van Waeyenberge4Frank Wiekhorst5https://orcid.org/0000-0003-0608-1473Jonathan Leliaert6https://orcid.org/0000-0001-8778-3092Physikalisch-Technische Bundesanstalt, Berlin, GermanyPhysikalisch-Technische Bundesanstalt, Berlin, GermanyPhysikalisch-Technische Bundesanstalt, Berlin, GermanyPhysikalisch-Technische Bundesanstalt, Berlin, GermanyDepartment of Solid State Sciences, Ghent University, Ghent, BelgiumPhysikalisch-Technische Bundesanstalt, Berlin, GermanyDepartment of Solid State Sciences, Ghent University, Ghent, BelgiumMagnetic nanoparticles have proven to be extremely useful in a broad range of biomedical applications. To ensure optimal efficiency, a precise characterization of these particles is required. Thermal Noise Magnetrometry (TNM) is a recently developed characterization technique that has already been validated against other techniques. TNM offers a unique advantage in that no external excitation of the system is required to drive the measurement. However, the extremely small stochastic signal in the femtotesla range currently limits the accessibility of the method, and a better understanding of the influences of the sample characteristics on the TNM signal is necessary. In this study, we present a theoretical framework to model the magnetic noise power properties of particle ensembles and their signal as measured via TNM. Both intrinsic sample properties (such as the number of particles or their volume) and the geometrical properties of the sample in the setup have been investigated numerically and validated with experiments. It is shown that the noise power depends linearly on the particle concentration, quadratically on the individual particle size, and linearly on the particle size for a constant total amount of magnetic material in the sample. Furthermore, an optimized sample shape is calculated for the given experimental geometry and subsequently 3d printed. This geometry produces a 3.5 fold increase in TNM signal (0.007 to 0.026 pT<sup>2</sup>) using less than half of the magnetic material considered in the intial measurements.https://ieeexplore.ieee.org/document/9505633/Biomedical materialmagnetic propertiesmagnetic nanoparticlesmagnetic noisethermal noise |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Katrijn Everaert Maik Liebl Dirk Gutkelch James Wells Bartel Van Waeyenberge Frank Wiekhorst Jonathan Leliaert |
spellingShingle |
Katrijn Everaert Maik Liebl Dirk Gutkelch James Wells Bartel Van Waeyenberge Frank Wiekhorst Jonathan Leliaert Noise Power Properties of Magnetic Nanoparticles as Measured in Thermal Noise Magnetometry IEEE Access Biomedical material magnetic properties magnetic nanoparticles magnetic noise thermal noise |
author_facet |
Katrijn Everaert Maik Liebl Dirk Gutkelch James Wells Bartel Van Waeyenberge Frank Wiekhorst Jonathan Leliaert |
author_sort |
Katrijn Everaert |
title |
Noise Power Properties of Magnetic Nanoparticles as Measured in Thermal Noise Magnetometry |
title_short |
Noise Power Properties of Magnetic Nanoparticles as Measured in Thermal Noise Magnetometry |
title_full |
Noise Power Properties of Magnetic Nanoparticles as Measured in Thermal Noise Magnetometry |
title_fullStr |
Noise Power Properties of Magnetic Nanoparticles as Measured in Thermal Noise Magnetometry |
title_full_unstemmed |
Noise Power Properties of Magnetic Nanoparticles as Measured in Thermal Noise Magnetometry |
title_sort |
noise power properties of magnetic nanoparticles as measured in thermal noise magnetometry |
publisher |
IEEE |
series |
IEEE Access |
issn |
2169-3536 |
publishDate |
2021-01-01 |
description |
Magnetic nanoparticles have proven to be extremely useful in a broad range of biomedical applications. To ensure optimal efficiency, a precise characterization of these particles is required. Thermal Noise Magnetrometry (TNM) is a recently developed characterization technique that has already been validated against other techniques. TNM offers a unique advantage in that no external excitation of the system is required to drive the measurement. However, the extremely small stochastic signal in the femtotesla range currently limits the accessibility of the method, and a better understanding of the influences of the sample characteristics on the TNM signal is necessary. In this study, we present a theoretical framework to model the magnetic noise power properties of particle ensembles and their signal as measured via TNM. Both intrinsic sample properties (such as the number of particles or their volume) and the geometrical properties of the sample in the setup have been investigated numerically and validated with experiments. It is shown that the noise power depends linearly on the particle concentration, quadratically on the individual particle size, and linearly on the particle size for a constant total amount of magnetic material in the sample. Furthermore, an optimized sample shape is calculated for the given experimental geometry and subsequently 3d printed. This geometry produces a 3.5 fold increase in TNM signal (0.007 to 0.026 pT<sup>2</sup>) using less than half of the magnetic material considered in the intial measurements. |
topic |
Biomedical material magnetic properties magnetic nanoparticles magnetic noise thermal noise |
url |
https://ieeexplore.ieee.org/document/9505633/ |
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1721204084868907008 |