INMAP overexpression inhibits cell proliferation, induces genomic instability and functions through p53/p21 pathways.

INMAP overexpression inhibits cell proliferation, induces genomic instability and functions through p53/p21 pathways.

INMAP is a spindle protein that plays essential role for mitosis, by ensuring spindle and centromere integrality. The aim of this study was to investigate the relevant functions of INMAP for genomic stability and its functional pathway. We overexpressed INMAP in HeLa cells, resulting in growth inhib...

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Bibliographic Details
Main Authors: Yan Zhu, Yan Lei, Baochen Du, Yanbo Zheng, Xiangfeng Lu, Tan Tan, Jingting Kang, Le Sun, Qianjin Liang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4312054?pdf=render

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