The second chance story of HIV-1 DNA: Unintegrated? Not a problem!
<p>Abstract</p> <p>Accumulation of high levels of unintegrated viral DNA is a common feature of retroviral infection. It was recently discovered that coinfection of cells with integrated and unintegrated HIV-1 can result in complementation, allowing viral replication in the absence...
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doaj-596b5a4729ee48e097e6f7f99c02a7de2020-11-25T01:58:20ZengBMCRetrovirology1742-46902008-07-01516110.1186/1742-4690-5-61The second chance story of HIV-1 DNA: Unintegrated? Not a problem!Wu Yuntao<p>Abstract</p> <p>Accumulation of high levels of unintegrated viral DNA is a common feature of retroviral infection. It was recently discovered that coinfection of cells with integrated and unintegrated HIV-1 can result in complementation, allowing viral replication in the absence of integration. This new mode of HIV-1 replication has numerous implications for the function of unintegrated viral DNA and its application as a therapeutic vector.</p> http://www.retrovirology.com/content/5/1/61 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Wu Yuntao |
spellingShingle |
Wu Yuntao The second chance story of HIV-1 DNA: Unintegrated? Not a problem! Retrovirology |
author_facet |
Wu Yuntao |
author_sort |
Wu Yuntao |
title |
The second chance story of HIV-1 DNA: Unintegrated? Not a problem! |
title_short |
The second chance story of HIV-1 DNA: Unintegrated? Not a problem! |
title_full |
The second chance story of HIV-1 DNA: Unintegrated? Not a problem! |
title_fullStr |
The second chance story of HIV-1 DNA: Unintegrated? Not a problem! |
title_full_unstemmed |
The second chance story of HIV-1 DNA: Unintegrated? Not a problem! |
title_sort |
second chance story of hiv-1 dna: unintegrated? not a problem! |
publisher |
BMC |
series |
Retrovirology |
issn |
1742-4690 |
publishDate |
2008-07-01 |
description |
<p>Abstract</p> <p>Accumulation of high levels of unintegrated viral DNA is a common feature of retroviral infection. It was recently discovered that coinfection of cells with integrated and unintegrated HIV-1 can result in complementation, allowing viral replication in the absence of integration. This new mode of HIV-1 replication has numerous implications for the function of unintegrated viral DNA and its application as a therapeutic vector.</p> |
url |
http://www.retrovirology.com/content/5/1/61 |
work_keys_str_mv |
AT wuyuntao thesecondchancestoryofhiv1dnaunintegratednotaproblem AT wuyuntao secondchancestoryofhiv1dnaunintegratednotaproblem |
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1724970217750134784 |