Novel ion exchange resin-based combination drug-delivery system for treatment of gastro esophageal reflux diseases

The present study involves preparation and characterization of a combination tablet of ranitidine in immediate release form and domperidone in sustained release form, using ion exchange resins. Ranitidine lowers acid secretion, while domperidone release over a prolonged period improves gastric motil...

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Bibliographic Details
Main Authors: Mangesh Ramesh Bhalekar, Nitin Madhukar Kadam, Nilam Hindurao Patil, Nitin Somnath Gawale, Ashwini Madgulkar
Format: Article
Language:English
Published: Universidade de São Paulo 2010-06-01
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502010000200021