Age-associated changes in oxidative stress and NAD+ metabolism in human tissue.

Age-associated changes in oxidative stress and NAD+ metabolism in human tissue.

Nicotinamide adenine dinucleotide (NAD(+)) is an essential electron transporter in mitochondrial respiration and oxidative phosphorylation. In genomic DNA, NAD(+) also represents the sole substrate for the nuclear repair enzyme, poly(ADP-ribose) polymerase (PARP) and the sirtuin family of NAD-depend...

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Bibliographic Details
Main Authors: Hassina Massudi, Ross Grant, Nady Braidy, Jade Guest, Bruce Farnsworth, Gilles J Guillemin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22848760/?tool=EBI

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