Diversity of breakpoints of variant Philadelphia chromosomes in chronic myeloid leukemia in Brazilian patients

Diversity of breakpoints of variant Philadelphia chromosomes in chronic myeloid leukemia in Brazilian patients

Background: Chronic myeloid leukemia is a myeloproliferative disorder characterized by the Philadelphia chromosome or t(9;22)(q34.1;q11.2), resulting in the break-point cluster regionAbelson tyrosine kinase fusion gene, which encodes a constitutively active tyrosine kinase protein. The Philadelphia...

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Bibliographic Details
Main Authors:	Maria de Lourdes Lopes Ferrari Chauffaille, Ana Carolina de Almeida Bandeira, Aline Schiavoni Guarnieri da Silva
Format:	Article
Language:	English
Published:	Elsevier 2015-02-01
Series:	Revista Brasileira de Hematologia e Hemoterapia
Subjects:	Leukemia myelogenous chronic BCR-ABL positive Philadelphia chromosome Chromosome breakpoints Oncogenes Brazil
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-84842015000100017&lng=en&tlng=en

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