Hepcidin is an antibacterial, stress-inducible peptide of the biliary system.

BACKGROUND/AIMS: Hepcidin (gene name HAMP), an IL-6-inducible acute phase peptide with antimicrobial properties, is the key negative regulator of iron metabolism. Liver is the primary source of HAMP synthesis, but it is also produced by other tissues such as kidney or heart and is found in body flui...

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Bibliographic Details
Main Authors: Pavel Strnad, Peggy Schwarz, Maria C D Rasenack, Ozlem Kucukoglu, Rayan I Habib, Dominik Heuberger, Robert Ehehalt, Michael W Müller, Adolf Stiehl, Guido Adler, Hasan Kulaksiz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3025980?pdf=render