Knockout of glutathione peroxidase 5 down-regulates the piRNAs in the caput epididymidis of aged mice

Knockout of glutathione peroxidase 5 down-regulates the piRNAs in the caput epididymidis of aged mice

The mammalian epididymis not only plays a fundamental role in the maturation of spermatozoa, but also provides protection against various stressors. The foremost among these is the threat posed by oxidative stress, which arises from an imbalance in reactive oxygen species and can elicit damage to ce...

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Bibliographic Details
Main Authors: Chen Chu, Lu Yu, Joelle Henry-Berger, Yan-Fei Ru, Ayhan Kocer, Alexandre Champroux, Zhi-Tong Li, Miao He, Sheng-Song Xie, Wu-Bin Ma, Min-Jie Ni, Zi-Mei Ni, Yun-Li Guo, Zhao-Liang Fei, Lan-Tao Gou, Qiang Liu, Samanta Sharma, Yu Zhou, Mo-Fang Liu, Charlie Degui Chen, Andrew L Eamens, Brett Nixon, Yu-Chuan Zhou, Joël R Drevet, Yong-Lian Zhang
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:Asian Journal of Andrology
Subjects:
epididymis; gpx5; oxidative stress; pirna; piwi-interacting rna; small noncoding rna
Online Access:http://www.ajandrology.com/article.asp?issn=1008-682X;year=2020;volume=22;issue=6;spage=590;epage=601;aulast=Chu

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