Critical appraisal of loteprednol ointment, gel, and suspension in the treatment of postoperative inflammation and pain following ocular and corneal transplant surgery
Amir Pirouzian,1,2 E Randy Craven1,21Department of Ophthalmology, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia; 2Wilmer Eye Institute, Johns Hopkins University, Baltimore, MD, USAPurpose: To review comprehensively the available peer-reviewed published articles in the literature on lote...
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2014-02-01
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doaj-592f1657244b489281aac21f3d75122f2020-11-24T22:32:53ZengDove Medical PressClinical Ophthalmology1177-54832014-02-012014default37938715746Critical appraisal of loteprednol ointment, gel, and suspension in the treatment of postoperative inflammation and pain following ocular and corneal transplant surgeryPirouzian ACraven ER Amir Pirouzian,1,2 E Randy Craven1,21Department of Ophthalmology, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia; 2Wilmer Eye Institute, Johns Hopkins University, Baltimore, MD, USAPurpose: To review comprehensively the available peer-reviewed published articles in the literature on loteprednol suspension, gel, and ointment in the treatment of ocular inflammation and pain following ocular surgery.Methods: We conducted a PubMed literature search review of all published articles on keywords associated with loteprednol etabonate and ocular surgery.Results: A total of 59 peer-reviewed articles were found in the literature. The focus of the majority of the articles was on the safety and efficacy of loteprednol etabonate 0.5% in post-operative control of inflammation and pain following cataract surgery. There were only three articles with a remote association between loteprednol etabonate and keratoplasty.Conclusion: Lotemax® ointment may also have potential as a first-line anti-inflammatory agent of choice in postoperative settings of strabismus and penetrating glaucoma, and following low-risk penetrating keratoplasty procedures.Keywords: loteprednol, inflammation, pain, keratoplasty, surgery, eyehttp://www.dovepress.com/critical-appraisal-of-loteprednol-ointment-gel-and-suspension-in-the-t-a15746 |
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DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Pirouzian A Craven ER |
spellingShingle |
Pirouzian A Craven ER Critical appraisal of loteprednol ointment, gel, and suspension in the treatment of postoperative inflammation and pain following ocular and corneal transplant surgery Clinical Ophthalmology |
author_facet |
Pirouzian A Craven ER |
author_sort |
Pirouzian A |
title |
Critical appraisal of loteprednol ointment, gel, and suspension in the treatment of postoperative inflammation and pain following ocular and corneal transplant surgery |
title_short |
Critical appraisal of loteprednol ointment, gel, and suspension in the treatment of postoperative inflammation and pain following ocular and corneal transplant surgery |
title_full |
Critical appraisal of loteprednol ointment, gel, and suspension in the treatment of postoperative inflammation and pain following ocular and corneal transplant surgery |
title_fullStr |
Critical appraisal of loteprednol ointment, gel, and suspension in the treatment of postoperative inflammation and pain following ocular and corneal transplant surgery |
title_full_unstemmed |
Critical appraisal of loteprednol ointment, gel, and suspension in the treatment of postoperative inflammation and pain following ocular and corneal transplant surgery |
title_sort |
critical appraisal of loteprednol ointment, gel, and suspension in the treatment of postoperative inflammation and pain following ocular and corneal transplant surgery |
publisher |
Dove Medical Press |
series |
Clinical Ophthalmology |
issn |
1177-5483 |
publishDate |
2014-02-01 |
description |
Amir Pirouzian,1,2 E Randy Craven1,21Department of Ophthalmology, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia; 2Wilmer Eye Institute, Johns Hopkins University, Baltimore, MD, USAPurpose: To review comprehensively the available peer-reviewed published articles in the literature on loteprednol suspension, gel, and ointment in the treatment of ocular inflammation and pain following ocular surgery.Methods: We conducted a PubMed literature search review of all published articles on keywords associated with loteprednol etabonate and ocular surgery.Results: A total of 59 peer-reviewed articles were found in the literature. The focus of the majority of the articles was on the safety and efficacy of loteprednol etabonate 0.5% in post-operative control of inflammation and pain following cataract surgery. There were only three articles with a remote association between loteprednol etabonate and keratoplasty.Conclusion: Lotemax® ointment may also have potential as a first-line anti-inflammatory agent of choice in postoperative settings of strabismus and penetrating glaucoma, and following low-risk penetrating keratoplasty procedures.Keywords: loteprednol, inflammation, pain, keratoplasty, surgery, eye |
url |
http://www.dovepress.com/critical-appraisal-of-loteprednol-ointment-gel-and-suspension-in-the-t-a15746 |
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