Critical appraisal of loteprednol ointment, gel, and suspension in the treatment of postoperative inflammation and pain following ocular and corneal transplant surgery

Amir Pirouzian,1,2 E Randy Craven1,21Department of Ophthalmology, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia; 2Wilmer Eye Institute, Johns Hopkins University, Baltimore, MD, USAPurpose: To review comprehensively the available peer-reviewed published articles in the literature on lote...

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Main Authors: Pirouzian A, Craven ER
Format: Article
Language:English
Published: Dove Medical Press 2014-02-01
Series:Clinical Ophthalmology
Online Access:http://www.dovepress.com/critical-appraisal-of-loteprednol-ointment-gel-and-suspension-in-the-t-a15746
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spelling doaj-592f1657244b489281aac21f3d75122f2020-11-24T22:32:53ZengDove Medical PressClinical Ophthalmology1177-54832014-02-012014default37938715746Critical appraisal of loteprednol ointment, gel, and suspension in the treatment of postoperative inflammation and pain following ocular and corneal transplant surgeryPirouzian ACraven ER Amir Pirouzian,1,2 E Randy Craven1,21Department of Ophthalmology, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia; 2Wilmer Eye Institute, Johns Hopkins University, Baltimore, MD, USAPurpose: To review comprehensively the available peer-reviewed published articles in the literature on loteprednol suspension, gel, and ointment in the treatment of ocular inflammation and pain following ocular surgery.Methods: We conducted a PubMed literature search review of all published articles on keywords associated with loteprednol etabonate and ocular surgery.Results: A total of 59 peer-reviewed articles were found in the literature. The focus of the majority of the articles was on the safety and efficacy of loteprednol etabonate 0.5% in post-operative control of inflammation and pain following cataract surgery. There were only three articles with a remote association between loteprednol etabonate and keratoplasty.Conclusion: Lotemax® ointment may also have potential as a first-line anti-inflammatory agent of choice in postoperative settings of strabismus and penetrating glaucoma, and following low-risk penetrating keratoplasty procedures.Keywords: loteprednol, inflammation, pain, keratoplasty, surgery, eyehttp://www.dovepress.com/critical-appraisal-of-loteprednol-ointment-gel-and-suspension-in-the-t-a15746
collection DOAJ
language English
format Article
sources DOAJ
author Pirouzian A
Craven ER
spellingShingle Pirouzian A
Craven ER
Critical appraisal of loteprednol ointment, gel, and suspension in the treatment of postoperative inflammation and pain following ocular and corneal transplant surgery
Clinical Ophthalmology
author_facet Pirouzian A
Craven ER
author_sort Pirouzian A
title Critical appraisal of loteprednol ointment, gel, and suspension in the treatment of postoperative inflammation and pain following ocular and corneal transplant surgery
title_short Critical appraisal of loteprednol ointment, gel, and suspension in the treatment of postoperative inflammation and pain following ocular and corneal transplant surgery
title_full Critical appraisal of loteprednol ointment, gel, and suspension in the treatment of postoperative inflammation and pain following ocular and corneal transplant surgery
title_fullStr Critical appraisal of loteprednol ointment, gel, and suspension in the treatment of postoperative inflammation and pain following ocular and corneal transplant surgery
title_full_unstemmed Critical appraisal of loteprednol ointment, gel, and suspension in the treatment of postoperative inflammation and pain following ocular and corneal transplant surgery
title_sort critical appraisal of loteprednol ointment, gel, and suspension in the treatment of postoperative inflammation and pain following ocular and corneal transplant surgery
publisher Dove Medical Press
series Clinical Ophthalmology
issn 1177-5483
publishDate 2014-02-01
description Amir Pirouzian,1,2 E Randy Craven1,21Department of Ophthalmology, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia; 2Wilmer Eye Institute, Johns Hopkins University, Baltimore, MD, USAPurpose: To review comprehensively the available peer-reviewed published articles in the literature on loteprednol suspension, gel, and ointment in the treatment of ocular inflammation and pain following ocular surgery.Methods: We conducted a PubMed literature search review of all published articles on keywords associated with loteprednol etabonate and ocular surgery.Results: A total of 59 peer-reviewed articles were found in the literature. The focus of the majority of the articles was on the safety and efficacy of loteprednol etabonate 0.5% in post-operative control of inflammation and pain following cataract surgery. There were only three articles with a remote association between loteprednol etabonate and keratoplasty.Conclusion: Lotemax® ointment may also have potential as a first-line anti-inflammatory agent of choice in postoperative settings of strabismus and penetrating glaucoma, and following low-risk penetrating keratoplasty procedures.Keywords: loteprednol, inflammation, pain, keratoplasty, surgery, eye
url http://www.dovepress.com/critical-appraisal-of-loteprednol-ointment-gel-and-suspension-in-the-t-a15746
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