Concepts, Challenges and Successes in Modeling Thermodynamics of Metabolism

The modeling of the chemical reactions involved in metabolism is a daunting task. Ideally, the modeling of metabolism would use kinetic simulations, but these simulations require knowledge of the thousands of rate constants involved in the reactions. The measurement of rate constants is very labor i...

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Bibliographic Details
Main Author: William R. Cannon
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-11-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fbioe.2014.00053/full