EXPERIENCE OF TREATMENT OF DIFFERENT FORMS OF EPILEPSY WITH GENERIC TOPIRAMATE (The results of focus observation in out-patientclinics network of Moscow city public healthcare services)

• Main Authors: O. L. Badalyan, M. A. Bogomazova, I. I. Zhuravleva, A. M. Ismailov, E. G. Komelkova, L. N. Lesinker, Yu. I. Logvinov, O. V. Otcheskaya, S. V. Petrov, Yu. V. Solomatin, A. М. Teplysheva, T. N. Udovuchenko, E. A. Khromykh, A. S. Chukanova, A. V. Lebedeva, S. G. Burd, A. N. Boiko
• Format: Article
• Language: Russian
• Published: IRBIS LLC 2016-09-01
• Series: Эпилепсия и пароксизмальные состояния
• Subjects: topiramate; generic; efficacy; tolerance; topsaver; topamax; epilepsy
• Online Access: https://www.epilepsia.su/jour/article/view/282
• ISSN: 2077-8333; 2311-4088

Current work is dedicated to analysis of treatment with generic topiramate in mono- as well as in polytherapy in patients with different forms of epilepsy. Forclinical assessmentsHospital Anxiety and Depression Scale (HADS), quality of life questionnaire for patients with epilepsy (QOLIE-10) and efficacy primary assessment based on decrease in frequency of seizures and adverse events before and after switching to generic topiramate were used. As a result of focus investigation switch to Topsaver was associated with maintenance of stable therapeutic effect in more, than 80% of cases. No negative dynamics in changes of HADS and QOLIE-10 points were observed.