A requirement of Polo-like kinase 1 in murine embryonic myogenesis and adult muscle regeneration

A requirement of Polo-like kinase 1 in murine embryonic myogenesis and adult muscle regeneration

Muscle development and regeneration require delicate cell cycle regulation of embryonic myoblasts and adult muscle satellite cells (MuSCs). Through analysis of the Polo-like kinase (Plk) family cell-cycle regulators in mice, we show that Plk1’s expression closely mirrors myoblast dynamics during emb...

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Bibliographic Details
Main Authors: Zhihao Jia, Yaohui Nie, Feng Yue, Yifan Kong, Lijie Gu, Timothy P Gavin, Xiaoqi Liu, Shihuan Kuang
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-08-01
Series:eLife
Subjects:
Plk1
BI2536
satellite cells
cell cycle
apoptosis
cell proliferation
Online Access:https://elifesciences.org/articles/47097

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