Instrumentation in Diffuse Optical Imaging
Diffuse optical imaging is highly versatile and has a very broad range of applications in biology and medicine. It covers diffuse optical tomography, fluorescence diffuse optical tomography, bioluminescence and a number of other new imaging methods. These methods of diffuse optical imaging have dive...
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doaj-590163d68ebb419890ece04e790ea50d2020-11-24T22:12:54ZengMDPI AGPhotonics2304-67322014-03-011193210.3390/photonics1010009photonics1010009Instrumentation in Diffuse Optical ImagingXiaofeng Zhang0Department of Radiology, Duke University Medical Center, DUMC 3808, Durham, NC 27710, USADiffuse optical imaging is highly versatile and has a very broad range of applications in biology and medicine. It covers diffuse optical tomography, fluorescence diffuse optical tomography, bioluminescence and a number of other new imaging methods. These methods of diffuse optical imaging have diversified instrument configurations, but share the same core physical principle: light propagation in highly diffusive media, i.e., biological tissue. In this review, the author summarizes the latest development in instrumentation and methodology available to diffuse optical imaging in terms of system architecture, light source, photo-detection, spectral separation, signal modulation and, lastly, imaging contrast.http://www.mdpi.com/2304-6732/1/1/9diffuse optical imaginginstrumentationfluorescencemolecular imagingbioluminescencetomographyclinicalpreclinical |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Xiaofeng Zhang |
spellingShingle |
Xiaofeng Zhang Instrumentation in Diffuse Optical Imaging Photonics diffuse optical imaging instrumentation fluorescence molecular imaging bioluminescence tomography clinical preclinical |
author_facet |
Xiaofeng Zhang |
author_sort |
Xiaofeng Zhang |
title |
Instrumentation in Diffuse Optical Imaging |
title_short |
Instrumentation in Diffuse Optical Imaging |
title_full |
Instrumentation in Diffuse Optical Imaging |
title_fullStr |
Instrumentation in Diffuse Optical Imaging |
title_full_unstemmed |
Instrumentation in Diffuse Optical Imaging |
title_sort |
instrumentation in diffuse optical imaging |
publisher |
MDPI AG |
series |
Photonics |
issn |
2304-6732 |
publishDate |
2014-03-01 |
description |
Diffuse optical imaging is highly versatile and has a very broad range of applications in biology and medicine. It covers diffuse optical tomography, fluorescence diffuse optical tomography, bioluminescence and a number of other new imaging methods. These methods of diffuse optical imaging have diversified instrument configurations, but share the same core physical principle: light propagation in highly diffusive media, i.e., biological tissue. In this review, the author summarizes the latest development in instrumentation and methodology available to diffuse optical imaging in terms of system architecture, light source, photo-detection, spectral separation, signal modulation and, lastly, imaging contrast. |
topic |
diffuse optical imaging instrumentation fluorescence molecular imaging bioluminescence tomography clinical preclinical |
url |
http://www.mdpi.com/2304-6732/1/1/9 |
work_keys_str_mv |
AT xiaofengzhang instrumentationindiffuseopticalimaging |
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