Colibactin in avian pathogenic Escherichia coli contributes to the development of meningitis in a mouse model

Colibactin in avian pathogenic Escherichia coli contributes to the development of meningitis in a mouse model

Colibactin is synthesized by a 54-kb genomic island, leads to toxicity in eukaryotic cells, and plays a vital role in many diseases, including neonatal sepsis and meningitis. Avian pathogenic Escherichia coli (APEC) is speculated to be an armory of extraintestinal pathogenic Escherichia coli and can...

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Bibliographic Details
Main Authors: Peili Wang, Jiaxiang Zhang, Yanfei Chen, Haoran Zhong, Heng Wang, Jianji Li, Guoqiang Zhu, Pengpeng Xia, Luying Cui, Jun Li, Junsheng Dong, Qingqing Gao, Xia Meng
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Virulence
Subjects:
colibactin
meningitis
escherichia coli
mouse model
clbh
Online Access:http://dx.doi.org/10.1080/21505594.2021.1972538

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