Cellular Angiofibroma of the Prostate: A Rare Tumor in an Unusual Location

Cellular Angiofibroma of the Prostate: A Rare Tumor in an Unusual Location

We report the unusual occurrence of a cellular angiofibroma in prostatic tissue. In this case, a 84-year-old man presented in the emergency room with urinary retention. Ultrasound revealed an enlarged prostate, which was suggestive for benign prostatic hyperplasia. The patient was treated with a Mi...

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Main Authors: Inez Wyn, Maria Debiec-Rychter, Ben Van Cleynenbreugel, Raf Sciot
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:Case Reports in Pathology
Online Access:http://dx.doi.org/10.1155/2014/871530
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spelling doaj-58e9a0564b47485a927cc79f5f064f362020-11-24T22:27:21ZengHindawi LimitedCase Reports in Pathology2090-67812090-679X2014-01-01201410.1155/2014/871530871530Cellular Angiofibroma of the Prostate: A Rare Tumor in an Unusual LocationInez Wyn0Maria Debiec-Rychter1Ben Van Cleynenbreugel2Raf Sciot3Department of Pathology, KU Leuven and University Hospitals Leuven, UZ Gasthuisberg, Herestraat 49, 3000 Leuven, BelgiumHuman Genetics, KU Leuven and University Hospitals Leuven, 3000 Leuven, BelgiumUrology, KU Leuven and University Hospitals Leuven, 3000 Leuven, BelgiumDepartment of Pathology, KU Leuven and University Hospitals Leuven, UZ Gasthuisberg, Herestraat 49, 3000 Leuven, BelgiumWe report the unusual occurrence of a cellular angiofibroma in prostatic tissue. In this case, a 84-year-old man presented in the emergency room with urinary retention. Ultrasound revealed an enlarged prostate, which was suggestive for benign prostatic hyperplasia. The patient was treated with a Millin retropubic prostatectomy. Macroscopically the prostate contained multiple circumscribed nodules. Microscopic examination of the tumor showed the appearance of cellular angiofibroma, consisting of bland spindle cells and prominent, hyalinized vessels. The diagnosis was supported by FISH, which revealed monoallelic loss of RB1/13q14 region, as seen in spindle cell lipoma, (extra-) mammary myofibroblastoma, and cellular angiofibroma. Cellular angiofibromas are rare, benign soft tissue tumours and were never reported in the prostatic gland.http://dx.doi.org/10.1155/2014/871530
collection DOAJ
language English
format Article
sources DOAJ
author Inez Wyn
Maria Debiec-Rychter
Ben Van Cleynenbreugel
Raf Sciot
spellingShingle Inez Wyn
Maria Debiec-Rychter
Ben Van Cleynenbreugel
Raf Sciot
Cellular Angiofibroma of the Prostate: A Rare Tumor in an Unusual Location
Case Reports in Pathology
author_facet Inez Wyn
Maria Debiec-Rychter
Ben Van Cleynenbreugel
Raf Sciot
author_sort Inez Wyn
title Cellular Angiofibroma of the Prostate: A Rare Tumor in an Unusual Location
title_short Cellular Angiofibroma of the Prostate: A Rare Tumor in an Unusual Location
title_full Cellular Angiofibroma of the Prostate: A Rare Tumor in an Unusual Location
title_fullStr Cellular Angiofibroma of the Prostate: A Rare Tumor in an Unusual Location
title_full_unstemmed Cellular Angiofibroma of the Prostate: A Rare Tumor in an Unusual Location
title_sort cellular angiofibroma of the prostate: a rare tumor in an unusual location
publisher Hindawi Limited
series Case Reports in Pathology
issn 2090-6781
2090-679X
publishDate 2014-01-01
description We report the unusual occurrence of a cellular angiofibroma in prostatic tissue. In this case, a 84-year-old man presented in the emergency room with urinary retention. Ultrasound revealed an enlarged prostate, which was suggestive for benign prostatic hyperplasia. The patient was treated with a Millin retropubic prostatectomy. Macroscopically the prostate contained multiple circumscribed nodules. Microscopic examination of the tumor showed the appearance of cellular angiofibroma, consisting of bland spindle cells and prominent, hyalinized vessels. The diagnosis was supported by FISH, which revealed monoallelic loss of RB1/13q14 region, as seen in spindle cell lipoma, (extra-) mammary myofibroblastoma, and cellular angiofibroma. Cellular angiofibromas are rare, benign soft tissue tumours and were never reported in the prostatic gland.
url http://dx.doi.org/10.1155/2014/871530
work_keys_str_mv AT inezwyn cellularangiofibromaoftheprostateararetumorinanunusuallocation
AT mariadebiecrychter cellularangiofibromaoftheprostateararetumorinanunusuallocation
AT benvancleynenbreugel cellularangiofibromaoftheprostateararetumorinanunusuallocation
AT rafsciot cellularangiofibromaoftheprostateararetumorinanunusuallocation
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