The KATP channel opener, nicorandil, ameliorates brain damage by modulating synaptogenesis after ischemic stroke.

With population growth and aging, more and more patients with cerebral infarction have varying degrees of disability. ATP-sensitive potassium (KATP) channels regulate many cellular functions by coupling metabolic status with cell membrane electrical activity. Nicorandil (N-(2-hydroxyethyl)-nicotinam...

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Bibliographic Details
Main Authors: Yuanzheng Zhao, Zhuoying Yang, Yuanhong He, Ruonan Sun, Heping Yuan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0246019