The VHL-dependent regulation of microRNAs in renal cancer

<p>Abstract</p> <p>Background</p> <p>The commonest histological type of renal cancer, clear cell renal cell carcinoma (cc RCC), is associated with genetic and epigenetic changes in the von Hippel-Lindau (VHL) tumour suppressor. VHL inactivation leads to induction of hyp...

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Bibliographic Details
Main Authors: Rawlings Lesley H, Michael Michael Z, Neal Calida S, Van der Hoek Mark B, Gleadle Jonathan M
Format: Article
Language:English
Published: BMC 2010-10-01
Series:BMC Medicine
Online Access:http://www.biomedcentral.com/1741-7015/8/64