Oxygen Concentration and Oxidative Stress Modulate the Influence of Alzheimer’s Disease Aβ1–42 Peptide on Human Cells

Oxygen Concentration and Oxidative Stress Modulate the Influence of Alzheimer’s Disease Aβ1–42 Peptide on Human Cells

Reactive oxygen species (ROS) generated after exposure to ionizing radiation and toxic peptides, in mitochondrial metabolism and during aging contribute to damage of cell’s structural and functional components and can lead to diseases. Monomers and small oligomers of amyloid beta (Aβ) peptide, playe...

Full description

Bibliographic Details
Main Authors:	Tamara Džinić, Norbert A. Dencher
Format:	Article
Language:	English
Published:	Hindawi Limited 2018-01-01
Series:	Oxidative Medicine and Cellular Longevity
Online Access:	http://dx.doi.org/10.1155/2018/7567959

Similar Items

In vitro fibrillization of Alzheimer’s amyloid-β peptide (1-42)
by: Ann Tiiman, et al.
Published: (2015-09-01)

Mechanism of neurotoxicity of Aβ42 peptide in Alzheimer's disease
by: Murakami, Kazuma
Published: (2011)

Influence of Hyperglycemic Conditions on Self-Association of the Alzheimer’s Amyloid β (Aβ1–42) Peptide
by: Sneha Menon, et al.
Published: (2017-05-01)

Dynamic Blood Concentrations of Aβ1–40 and Aβ1–42 in Alzheimer’s Disease
by: Yuan-Han Yang, et al.
Published: (2020-08-01)

The Aβ(1–38) peptide is a negative regulator of the Aβ(1–42) peptide implicated in Alzheimer disease progression
by: Maa O. Quartey, et al.
Published: (2021-01-01)

Dynamics of protofibril elongation and association involved in Aβ42 peptide aggregation in Alzheimer’s disease
by: Datta Bhaswati, et al.
Published: (2010-10-01)

Preclinical Alzheimer disease: Brain oxidative stress, Aβ peptide and proteomics
by: Christopher D. Aluise, et al.
Published: (2010-08-01)

Cerebrospinal fluid Aβ40 improves the interpretation of Aβ42 concentration for diagnosing Alzheimer’s disease.
by: Aline eDorey, et al.
Published: (2015-11-01)

Paper-Based Detection Device for Alzheimer’s Disease—Detecting β-amyloid Peptides (1–42) in Human Plasma
by: Wei-Hsuan Sung, et al.
Published: (2020-04-01)

Interplay of ionizing radiation, oxygen, ROS and age-associated diseases
by: Džinić, Tamara
Published: (2017)

The Alzheimer’s Disease γ-Secretase Generates Higher 42:40 Ratios for β-Amyloid Than for p3 Peptides
by: Gabriele Siegel, et al.
Published: (2017-06-01)

Modulation of Alzheimer's amyloid β peptide self-assembly : Insights into molecular mechanisms of peptide aggregation associated with Alzheimer's disease
by: Abelein, Axel
Published: (2015)

SINGLE-MOLECULE ANALYSIS OF ALZHEIMER'S β-PEPTIDE OLIGOMER DISASSEMBLY AT PHYSIOLOGICAL CONCENTRATION
by: Chen, Chen
Published: (2014)

Small-molecule induction of Aβ-42 peptide production in human cerebral organoids to model Alzheimer's disease associated phenotypes.
by: Serena Pavoni, et al.
Published: (2018-01-01)

A novel study on amyloid β peptide 40, 42 and 40/42 ratio in Saudi autistics
by: Al- Ayadhi Laila Y, et al.
Published: (2012-01-01)

Site-specific structural order in Alzheimer's Aβ42 fibrils
by: Hongsu Wang, et al.
Published: (2018-01-01)

Modeling human Aβ42 toxicity in Drosophila for Alzheimer's disease
by: Huang, Yu Han, et al.
Published: (2015)

(-)-cis-Carveol, a Natural Compound, Improves β-Amyloid-Peptide 1-42-Induced Memory Impairment and Oxidative Stress in the Rat Hippocampus
by: Lucian Hritcu, et al.
Published: (2020-01-01)

Dietary Modulation of Oxidative Stress in Alzheimer’s Disease
by: Arjun Thapa, et al.
Published: (2017-07-01)

Aβ43 in human Alzheimer’s disease: effects of active Aβ42 immunization
by: Lieke Jäkel, et al.
Published: (2019-09-01)

Derivation of cutoffs for the Elecsys® amyloid β (1–42) assay in Alzheimer's disease
by: Leslie M. Shaw, et al.
Published: (2018-01-01)

Plasma level of Amyloid β42 Is independent of neuronal function in Alzheimer's Disease
by: Dimitriadis Athanasios S, et al.
Published: (2008-04-01)

Microglial alterations in human Alzheimer's disease following Aβ42 immunization
by: Zotova, Elina, et al.
Published: (2011)

Automation vs. Experience: Measuring Alzheimer’s Beta-Amyloid 1–42 Peptide in the CSF
by: Alexander L. Kollhoff, et al.
Published: (2018-08-01)

Modulation of amyloid β peptide self-assembly : Aggregation mechanisms associated with Alzheimer's disease
by: Abelein, Axel
Published: (2013)

Synergistic Effect on Neurodegeneration by N-Truncated Aβ4−42 and Pyroglutamate Aβ3−42 in a Mouse Model of Alzheimer's Disease
by: Jose S. Lopez-Noguerola, et al.
Published: (2018-03-01)

Oxygen Concentration-Dependent Oxidative Stress Levels in Rats
by: Fumiko Nagatomo, et al.
Published: (2012-01-01)

Aggregation states of Aβ1-40, Aβ1-42 and Aβp3-42 amyloid beta peptides: a SANS study
by: Festa, Giulia, et al.
Published: (2020)

Reduced levels of Aβ 40 and Aβ 42 in brains of smoking controls and Alzheimer's patients
by: E Hellström-Lindahl, et al.
Published: (2004-03-01)

Cu(2+) affects amyloid-β (1-42) aggregation by increasing peptide-peptide binding forces.
by: Francis Hane, et al.
Published: (2013-01-01)

Reciprocal modulation of Aβ42 aggregation by copper and homocysteine
by: Salla eKeskitalo, et al.
Published: (2014-09-01)

NAP and D-SAL: neuroprotection against the β amyloid peptide (1–42)
by: Piltzer Inbar, et al.
Published: (2008-12-01)

RNA oxidation adducts 8-OHG and 8-OHA change with Aβ42 levels in late-stage Alzheimer's disease.
by: Adam M Weidner, et al.
Published: (2011-01-01)

A Specific Reduction in Aβ1−42 vs. a Universal Loss of Aβ Peptides in CSF Differentiates Alzheimer's Disease From Meningitis and Multiple Sclerosis
by: Philipp Spitzer, et al.
Published: (2018-05-01)

A Novel Cardenolide Glycoside Isolated from <i>Xysmalobium undulatum</i> Reduces Levels of the Alzheimer’s Disease-Associated β-Amyloid Peptides Aβ42 In Vitro
by: Anuradha Thakur, et al.
Published: (2021-07-01)

Systematic Aβ Analysis in Drosophila Reveals High Toxicity for the 1-42, 3-42 and 11-42 Peptides, and Emphasizes N- and C-Terminal Residues.
by: Maria Jonson, et al.
Published: (2015-01-01)

Inflammatory components in human Alzheimer's disease and after active amyloid-β42 immunization
by: Zotova, E., et al.
Published: (2013)

Advantages and disadvantages of the use of the CSF Amyloid β (Aβ) 42/40 ratio in the diagnosis of Alzheimer’s Disease
by: Oskar Hansson, et al.
Published: (2019-04-01)

Alzheimer’s Disease-associated peptide Aβ42 mobilises ER Ca2+ via InsP3R-dependent and -independent mechanisms
by: Laura E Allan, et al.
Published: (2013-11-01)

A multifunctional peptide rescues memory deficits in Alzheimer's disease transgenic mice by inhibiting Aβ42-induced cytotoxicity and increasing microglial phagocytosis
by: Di Xue, et al.
Published: (2012-06-01)