Intervertebral disc response to stem cell treatment is conditioned by disc state and cell carrier: An ex vivo study

Intervertebral disc response to stem cell treatment is conditioned by disc state and cell carrier: An ex vivo study

In vitro and in vivo studies evidenced that mesenchymal stem cells (MSCs) contribute to intervertebral disc (IVD) regeneration by differentiation towards the disc phenotype and matrix synthesis and/or by paracrine signalling to endogenous cells, thereby promoting a healthier disc phenotype in degene...

Full description

Bibliographic Details
Main Authors: Marianna Peroglio, Luzia Simone Douma, Tansinee Stephanie Caprez, Milena Janki, Lorin Michael Benneker, Mauro Alini, Sibylle Grad
Format: Article
Language:English
Published: Elsevier 2017-04-01
Series:Journal of Orthopaedic Translation
Subjects:
anabolism
bioreactor
degeneration
fibrin
nucleotomy
saline
Online Access:http://www.sciencedirect.com/science/article/pii/S2214031X17300104

Similar Items

Similar Items