Intervertebral disc response to stem cell treatment is conditioned by disc state and cell carrier: An ex vivo study
In vitro and in vivo studies evidenced that mesenchymal stem cells (MSCs) contribute to intervertebral disc (IVD) regeneration by differentiation towards the disc phenotype and matrix synthesis and/or by paracrine signalling to endogenous cells, thereby promoting a healthier disc phenotype in degene...
Main Authors: | , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2017-04-01
|
Series: | Journal of Orthopaedic Translation |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2214031X17300104 |