Association of 5-methylcytosine and 5-hydroxymethylcytosine with mitochondrial DNA content and clinical and biochemical parameters in hepatocellular carcinoma.

Increasing epidemiological evidence has indicated that inherited variations of mitochondrial DNA (mtDNA) copy number affect the genetic susceptibility of many malignancies in a tumour-specific manner and that DNA methylation also plays an important role in controlling gene expression during the diff...

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Bibliographic Details
Main Authors: Fan Shen, Wei Huang, Jia-Hui Qi, Bi-Feng Yuan, Jing-Tao Huang, Xin Zhou, Yu-Qi Feng, Ying-Juan Liu, Song-Mei Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24143196/?tool=EBI