The Use of Topical Tacrolimus 0.1% Skin Ointment for Anterior Segment Conditions: A Case Series

The Use of Topical Tacrolimus 0.1% Skin Ointment for Anterior Segment Conditions: A Case Series

Tacrolimus (FK 506) is a macrolactam derivative with immunomodulatory and anti-inflammatory activity. Topical tacrolimus 0.03% has been used for inflammatory conditions of the anterior segment. This article adds to the literature on the off-license application of tacrolimus ointment, by describing t...

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Main Authors: Poorna Abeysiri, Nicholas R. Johnston, Anthony C.B. Molteno
Format: Article
Language:English
Published: SAGE Publishing 2010-01-01
Series:Ophthalmology and Eye Diseases
Online Access:https://doi.org/10.1177/117917211000200001
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spelling doaj-588bd5523c3d4111b5a400dd705732e52020-11-24T20:44:05ZengSAGE PublishingOphthalmology and Eye Diseases1179-17212010-01-01210.1177/117917211000200001The Use of Topical Tacrolimus 0.1% Skin Ointment for Anterior Segment Conditions: A Case SeriesPoorna Abeysiri0Nicholas R. Johnston1Anthony C.B. Molteno2Dunedin Eye Department, Dunedin Hospital, Dunedin, Otago, New Zealand.Dunedin Eye Department, Dunedin Hospital, Dunedin, Otago, New Zealand.Dunedin Eye Department, Dunedin Hospital, Dunedin, Otago, New Zealand.Tacrolimus (FK 506) is a macrolactam derivative with immunomodulatory and anti-inflammatory activity. Topical tacrolimus 0.03% has been used for inflammatory conditions of the anterior segment. This article adds to the literature on the off-license application of tacrolimus ointment, by describing the safe and effective use of the higher strength of 0.1% topical tacrolimus skin ointment in four patients. To our knowledge this is the first report of topical tacrolimus 0.1% ointment applied to the conjunctival sac for the treatment of atopic keratoconjunctivitis, vernal keratoconjunctivitis and the post-operative management of trabeculectomy and graft rejection in steroid responders.https://doi.org/10.1177/117917211000200001
collection DOAJ
language English
format Article
sources DOAJ
author Poorna Abeysiri
Nicholas R. Johnston
Anthony C.B. Molteno
spellingShingle Poorna Abeysiri
Nicholas R. Johnston
Anthony C.B. Molteno
The Use of Topical Tacrolimus 0.1% Skin Ointment for Anterior Segment Conditions: A Case Series
Ophthalmology and Eye Diseases
author_facet Poorna Abeysiri
Nicholas R. Johnston
Anthony C.B. Molteno
author_sort Poorna Abeysiri
title The Use of Topical Tacrolimus 0.1% Skin Ointment for Anterior Segment Conditions: A Case Series
title_short The Use of Topical Tacrolimus 0.1% Skin Ointment for Anterior Segment Conditions: A Case Series
title_full The Use of Topical Tacrolimus 0.1% Skin Ointment for Anterior Segment Conditions: A Case Series
title_fullStr The Use of Topical Tacrolimus 0.1% Skin Ointment for Anterior Segment Conditions: A Case Series
title_full_unstemmed The Use of Topical Tacrolimus 0.1% Skin Ointment for Anterior Segment Conditions: A Case Series
title_sort use of topical tacrolimus 0.1% skin ointment for anterior segment conditions: a case series
publisher SAGE Publishing
series Ophthalmology and Eye Diseases
issn 1179-1721
publishDate 2010-01-01
description Tacrolimus (FK 506) is a macrolactam derivative with immunomodulatory and anti-inflammatory activity. Topical tacrolimus 0.03% has been used for inflammatory conditions of the anterior segment. This article adds to the literature on the off-license application of tacrolimus ointment, by describing the safe and effective use of the higher strength of 0.1% topical tacrolimus skin ointment in four patients. To our knowledge this is the first report of topical tacrolimus 0.1% ointment applied to the conjunctival sac for the treatment of atopic keratoconjunctivitis, vernal keratoconjunctivitis and the post-operative management of trabeculectomy and graft rejection in steroid responders.
url https://doi.org/10.1177/117917211000200001
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