Ginseng gintonin alleviates neurological symptoms in the G93A-SOD1 transgenic mouse model of amyotrophic lateral sclerosis through lysophosphatidic acid 1 receptor

Ginseng gintonin alleviates neurological symptoms in the G93A-SOD1 transgenic mouse model of amyotrophic lateral sclerosis through lysophosphatidic acid 1 receptor

Background: We recently showed that gintonin, an active ginseng ingredient, exhibits antibrain neurodegenerative disease effects including multiple target mechanisms such as antioxidative stress and antiinflammation via the lysophosphatidic acid (LPA) receptors. Amyotrophic lateral sclerosis (ALS) i...

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Bibliographic Details
Main Authors: Sung Min Nam, Jong Hee Choi, Sun-Hye Choi, Hee-Jung Cho, Yeon-Jin Cho, Hyewhon Rhim, Hyoung-Chun Kim, Ik-Hyun Cho, Do-Geun Kim, Seung-Yeol Nah
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:Journal of Ginseng Research
Subjects:
ALS
ginseng
gintonin
motor activity
spinal cord
Online Access:http://www.sciencedirect.com/science/article/pii/S1226845320300865

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http://www.sciencedirect.com/science/article/pii/S1226845320300865

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