Pilot Evaluation of Two <i>Fasciola hepatica</i> Biomarkers for Supporting Triclabendazole (TCBZ) Efficacy Diagnostics

Pilot Evaluation of Two <i>Fasciola hepatica</i> Biomarkers for Supporting Triclabendazole (TCBZ) Efficacy Diagnostics

<i>Fasciola hepatica</i>, the causative agent of fasciolosis, is a global threat to public health, animal welfare, agricultural productivity, and food security. In the ongoing absence of a commercial vaccine, independent emergences of anthelmintic-resistant parasite populations worldwide...

Full description

Bibliographic Details
Main Authors:	Clare F. Collett, Russell M. Morphew, David Timson, Helen C. Phillips, Peter M. Brophy
Format:	Article
Language:	English
Published:	MDPI AG 2020-07-01
Series:	Molecules
Subjects:	fasciolosis triclabendazole diagnostics biomarker calreticulin triose phosphate isomerase
Online Access:	https://www.mdpi.com/1420-3049/25/15/3477

Similar Items

In vitro biomarker discovery in the parasitic flatworm Fasciola hepatica for monitoring chemotherapeutic treatment
by: Russell M. Morphew, et al.
Published: (2014-06-01)

In Vtro Effects of Triclabendazole (TCBZ) on the Excretory-Secretory Products (ESP) of Fasciola Spp Parasites
by: Taghi Golmohamdi, et al.
Published: (2012-03-01)

In vitro Effects of Triclabendazole (TCBZ) on the Excretory-Secretory Products (ESP) of Fasciola spp Parasites
by: Ali Farahnak, et al.
Published: (2012-03-01)

Study of Triclabendazole (TCBZ) Effect on Aspartate Transaminase (AST) Activity of Fasciola gigantica Parasite and Liver Enzyme Activity Assay
by: Shima Shafaei, et al.
Published: (2015-10-01)

Fasciola Hepatica Induced Hepatic Abscess Treated with Triclabendazole
by: Hyun Joon Park, et al.
Published: (2021-01-01)

Caracterização funcional da proteína Triose fosfato isomerase de Paracoccidioides brasiliensis como potencial adesina
by: Pereira, Luiz Augusto
Published: (2015)

Сommission test of Effectiveness of the supramolecular complex based on triclabendazole and albendazole at Fasciolosis and gastrointestinal strongylatosis of sheep
by: E. V. Lagereva, et al.
Published: (2020-06-01)

EFFICACY OF SUPRAMOLECULAR COMPLEX BASED ON ALBENDAZOLE AND TRICLABENDAZOLE AGAINST FASCIOLOSIS AND GASTRO-INTESTINAL NEMATODOSIS OF SHEEP
by: E. V. Lagereva, et al.
Published: (2019-09-01)

Apparent Triclabendazole-Resistant Human Fasciola hepatica Infection, the Netherlands
by: Annemarie J.S. Winkelhagen, et al.
Published: (2012-06-01)

Study of the Effectiveness of a Supramolecular Complex Based on Albendazole and Triclabendazole (Altric-Extra) Against Nematodes of the Digestive Tract and Fasciola spp. in Sheep Under Production Conditions
by: E. V. Lagereva, et al.
Published: (2020-03-01)

Triclabendazole Effect on Protease Enzyme Activity in the Excretory- Secretory Products of Fasciola hepatica in Vitro
by: Yosef Shrifi, et al.
Published: (2014-03-01)

Étude structurale et fonctionnelle d’une sérine/thréonine kinase de staphylococcus aureus
by: Paracuellos torrecilla, Patricia
Published: (2009)

The Effect of Triclabendazole on ALT Enzyme activity in Fasciola hepatica helminths and parasitized sheep liver tissues
by: Ali Farahnak, et al.
Published: (2015-01-01)

MORPHOFUNCTIONAL PECULIARITIES OF FASCIOLA HEPATICA ORGANS CHANGES AFTER TREATMENT OF SHEEP WITH TRICLABENDAZOLE IN CASE OF FASCIOLOSIS
by: O. I. Bibik, et al.
Published: (2019-09-01)

Prevalence and genetic characterization of Giardia lamblia in relation to diarrhea in Limpopo and Gauteng provinces, South Africa
by: Amidou Samie, et al.
Published: (2020-05-01)

Triclabendazole Treatment Failure for Fasciola hepatica Infection among Preschool and School-Age Children, Cusco, Peru
by: Maria L. Morales, et al.
Published: (2021-07-01)

Triclabendazole (Anthelmintic Drug) Effects on the Excretory- Secretory Proteome of Fasciola hepatica in Two Dimension Electrophoresis Gel
by: Ashkan Faridi, et al.
Published: (2014-06-01)

Protective Immune Responses Generated in a Murine Model Following Immunization with Recombinant Schistosoma japonicum Insulin Receptor
by: Hong You, et al.
Published: (2018-10-01)

The interaction of silver nanoparticles with triosephosphate isomerase from human and malarial parasite (Plasmodium falciparum) : a comparative study
by: De Moor, Warren Ralph Josephus
Published: (2014)

Study of triclabendazole effects on Fasciola hepatica’s life-supporting organs, spines and suckers responsible for stable position of the parasite in the host
by: O. I. Bibik, et al.
Published: (2021-09-01)

Clonal amplification of Fasciola hepatica in Galba truncatula: within and between isolate variation of triclabendazole-susceptible and -resistant clones
by: Jane E. Hodgkinson, et al.
Published: (2018-06-01)

Fasciola hepatica: Histology of the Reproductive Organs and Differential Effects of Triclabendazole on Drug-Sensitive and Drug-Resistant Fluke Isolates and on Flukes from Selected Field Cases
by: Robert Hanna
Published: (2015-06-01)

Alteration in Haematological and Liver Function Indices during Human Infection with Fasciola spp. Post Treatment with Triclabendazole
by: Mohammad Ismaeil Edalatzadeh, et al.
Published: (2006-09-01)

Early mitochondrial dysfunction leads to altered redox chemistry underlying pathogenesis of TPI deficiency
by: Stacy L. Hrizo, et al.
Published: (2013-06-01)

Fasciola Hepatica Case with Hemobilia
by: Ibrahim Halil Bahcecioglu, et al.
Published: (2007-01-01)

Effect of Triclabendazole and Dexamethasone on Ovine Fascioliasis
by: Oday K. Luaibi
Published: (2013-12-01)

Assessment of Antibilharzial and Biochemical Effects of Triclabendazol in Experimental Schistomiasis
by: Nadia Abou El-Ela, et al.
Published: (2008-03-01)

Antisperm protein targets in azoospermia men
by: Mohammad-Sadegh Soltani Zangbar, et al.
Published: (2016-01-01)

Distribution and factors associated with Fasciola hepatica infection in cattle in the south of Espírito Santo State, Brazil
by: Alves DP, et al.
Published: (2011-01-01)

Seasonal and Age Dynamics of Infection of Cattle and Sheep with <i>Fasciola hepatica</i> in the Territory of the Bryansk Region
by: A. N. Postevoy
Published: (2020-05-01)

Transcriptome assembly dataset of anthelmintic response in Fasciola hepatica
by: Estefan Miranda-Miranda, et al.
Published: (2021-04-01)

"Evaluation of a Pre-Selected Epitope of Fasciola hepatica Cathepsin- L1 for the Diagnosis of Human Fasciolosis by IgG-ELISA Test."
by: MB Rokni, et al.
Published: (2002-09-01)

"Evaluation of a Pre-Selected Epitope of Fasciola hepatica Cathepsin- L1 for the Diagnosis of Human Fasciolosis by IgG-ELISA Test."
by: MB Rokni, et al.
Published: (2002-12-01)

Fasciola hepatica em ovinos, caprinos e bubalinos em municípios do sul do Espírito Santo
by: Milena Batista Carneiro, et al.

The Statistical Analysis of Pharmacokinetic Parameters in the Context of Bioequivalence Testing of Two Anthelmintic Formulas Based on Ivermectine and Triclabendazole in Sheep
by: Farczadi Lenard, et al.
Published: (2019-06-01)

Study on Glutathione S-Transferase (GST) Inhibition Assay by Triclabendazole. І: Protoscoleces (Hydatid Cyst; Echinococcus granulosus) and Sheep Liver Tissue
by: MA Seyyedi, et al.
Published: (2005-06-01)

Study on Glutathione S-Transferase (GST) Inhibition Assay by Triclabendazole. І: Protoscoleces (Hydatid Cyst; Echinococcus granulosus) and Sheep Liver Tissue
by: MA Seyyedi, et al.
Published: (2005-03-01)

Serologic detection of antibodies against Fasciola hepatica in sheep in the middle Black Sea region of Turkey
by: Mustafa Acici, et al.
Published: (2017-06-01)

Fasciola hepatica Control Practices on a Sample of Dairy Farms in Victoria, Australia
by: Jane M. Kelley, et al.
Published: (2021-06-01)

Prevalence and Molecular Diagnosis of Fasciola hepatica in Sheep and Goats in Different Districts of Punjab, Pakistan
by: Waseem Shahzad*, Khalid Mehmood1, Rashid Munir2, Waqar Aslam, Muhammad Ijaz1, Rashid Ahmad, Mohammad Sarwar Khan1 and Ahmad Jawad Sabir1
Published: (2012-10-01)