Disease Modifying Effects of the Spider Toxin Parawixin2 in the Experimental Epilepsy Model

Disease Modifying Effects of the Spider Toxin Parawixin2 in the Experimental Epilepsy Model

(1) Background: Temporal lobe epilepsy (TLE) is the most common type of epilepsy in adults. It is also the one with the highest percentage of drug-resistance to the current available anti-epileptic drugs (AED). Additionaly, most antiepileptic drugs are only able to control seizures in epileptogenesi...

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Bibliographic Details
Main Authors: Lívea Dornela Godoy, José Luiz Liberato, Marcus Vinícius Batista Celani, Leonardo Gobbo-Neto, Norberto Peporine Lopes, Wagner Ferreira dos Santos
Format: Article
Language:English
Published: MDPI AG 2017-08-01
Series:Toxins
Subjects:
lithium-pilocarpine model
temporal lobe epilepsy
Parvalbumin
GABA transporter inhibitor
neuroprotection
hippocampus
Spider toxin
Parawixia bistriata
Tiagabine
Online Access:https://www.mdpi.com/2072-6651/9/9/262

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