Lectins offer new perspectives in the development of macrophage-targeted therapies for COPD/emphysema.

Lectins offer new perspectives in the development of macrophage-targeted therapies for COPD/emphysema.

We have previously shown that the defective ability of alveolar macrophages (AM) to phagocytose apoptotic cells ('efferocytosis') in chronic obstructive pulmonary disease/emphysema (COPD) could be therapeutically improved using the C-type lectin, mannose binding lectin (MBL), although the...

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Bibliographic Details
Main Authors: Violet R Mukaro, Johan Bylund, Greg Hodge, Mark Holmes, Hubertus Jersmann, Paul N Reynolds, Sandra Hodge
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23441163/?tool=EBI

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