C-Type Lectin Receptor (CLR)–Fc Fusion Proteins As Tools to Screen for Novel CLR/Bacteria Interactions: An Exemplary Study on Preselected Campylobacter jejuni Isolates

C-Type Lectin Receptor (CLR)–Fc Fusion Proteins As Tools to Screen for Novel CLR/Bacteria Interactions: An Exemplary Study on Preselected Campylobacter jejuni Isolates

C-type lectin receptors (CLRs) are carbohydrate-binding receptors that recognize their ligands often in a Ca2+-dependent manner. Upon ligand binding, myeloid CLRs in innate immunity trigger or inhibit a variety of signaling pathways, thus initiating or modulating effector functions such as cytokine...

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Bibliographic Details
Main Authors: Sabine Mayer, Rebecca Moeller, João T. Monteiro, Kerstin Ellrott, Christine Josenhans, Bernd Lepenies
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Immunology
Subjects:
C-type lectin receptors
Campylobacter jejuni
innate immunity
flow cytometry
confocal microscopy
ELISA assay
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00213/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2018.00213/full

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