Gadolinium increases the vascular reactivity of rat aortic rings

Gadolinium increases the vascular reactivity of rat aortic rings

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Gadolinium (Gd) blocks intra- and extracellular ATP hydrolysis. We determined whether Gd affects vascular reactivity to contractile responses to phenylephrine (PHE) by blocking aortic ectonucleoside triphosphate diphosphohydrolase (E-NTPDase). Wistar rats of both sexes (260-300 g, 23 females, 7 male...

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Bibliographic Details
Main Authors: J.K. Angeli, D.B. Ramos, E.A. Casali, D.O.G. Souza, J.J.F. Sarkis, I. Stefanon, D.V. Vassallo, C.R. Fürstenau
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2011-05-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Gadolinium
E-NTPDase
Adenosine
Angiotensin II
AT1receptor
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2011000500010

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2011000500010

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