Amelioration of experimental autoimmune encephalomyelitis by clozapine is not associated with defective CD4 T cell responses
Abstract Atypical antipsychotic agents, such as clozapine, are used for treating psychosis and depression and have recently been found to modulate neuroinflammation. We have shown previously that treatment of mice with the atypical antipsychotic agents, clozapine or risperidone, attenuates disease s...
Main Authors: | Pirooz Zareie, Bronwen Connor, Anne Camille La Flamme |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2017-03-01
|
Series: | Journal of Neuroinflammation |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12974-017-0842-5 |
Similar Items
-
Clozapine reduces infiltration into the CNS by targeting migration in experimental autoimmune encephalomyelitis
by: Katharina Robichon, et al.
Published: (2020-02-01) -
Systemic administration of orexin A ameliorates established experimental autoimmune encephalomyelitis by diminishing neuroinflammation
by: Laurine Becquet, et al.
Published: (2019-03-01) -
MAdCAM-1-Mediated Intestinal Lymphocyte Homing Is Critical for the Development of Active Experimental Autoimmune Encephalomyelitis
by: Kristina Kuhbandner, et al.
Published: (2019-04-01) -
Dimethyl itaconate, an itaconate derivative, exhibits immunomodulatory effects on neuroinflammation in experimental autoimmune encephalomyelitis
by: Ping-Chang Kuo, et al.
Published: (2020-04-01) -
4-Ethylguaiacol modulates neuroinflammation and Th1/Th17 differentiation to ameliorate disease severity in experimental autoimmune encephalomyelitis
by: Wen-Tsan Weng, et al.
Published: (2021-05-01)