IFN-γ-stimulated neutrophils suppress lymphocyte proliferation through expression of PD-L1.

IFN-γ-stimulated neutrophils suppress lymphocyte proliferation through expression of PD-L1.

During systemic inflammation different neutrophil subsets are mobilized to the peripheral blood. These neutrophil subsets can be distinguished from normal circulating neutrophils (CD16(bright)/CD62L(bright)), based on either an immature CD16(dim)/CD62L(bright) or a CD16(bright)/CD62L(dim) phenotype....

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Bibliographic Details
Main Authors: Stan de Kleijn, Jeroen D Langereis, Jenneke Leentjens, Matthijs Kox, Mihai G Netea, Leo Koenderman, Gerben Ferwerda, Peter Pickkers, Peter W M Hermans
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3756078?pdf=render

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