<i>Graptopetalum paraguayense</i> Inhibits Liver Fibrosis by Blocking TGF-β Signaling In Vivo and In Vitro

<i>Graptopetalum paraguayense</i> Inhibits Liver Fibrosis by Blocking TGF-β Signaling In Vivo and In Vitro

Background and Aims: Liver fibrosis is the excessive accumulation of extracellular matrix proteins, including collagen, which occurs in most types of chronic liver diseases. Advanced liver fibrosis results in cirrhosis, liver failure, and portal hypertension. Activated hepatic perivascular stellate...

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Main Authors: Wei-Hsiang Hsu, Se-Chun Liao, Yau-Jan Chyan, Kai-Wen Huang, Shih-Lan Hsu, Yi-Chen Chen, Ma-Li Siu, Chia-Chuan Chang, Yuh-Shan Chung, Chi-Ying F. Huang
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:International Journal of Molecular Sciences
Subjects:
<i>Graptopetalum paraguayense</i>
liver fibrosis
hepatic stellate cell
TGF-β
Online Access:https://www.mdpi.com/1422-0067/20/10/2592

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