Evaluation of Single-Cell Cytokine Secretion and Cell-Cell Interactions with a Hierarchical Loading Microwell Chip
Summary: Comprehensive evaluation of single T cell functions such as cytokine secretion and cytolysis of target cells is greatly needed in adoptive cell therapy (ACT) but has never been fully fulfilled by current approaches. Herein, we develop a hierarchical loading microwell chip (HL-Chip) that ali...
Main Authors: | Yufu Zhou, Ning Shao, Ricardo Bessa de Castro, Pengchao Zhang, Yuan Ma, Xin Liu, Feizhou Huang, Rong-Fu Wang, Lidong Qin |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2020-04-01
|
Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124720305234 |
Similar Items
-
Single-Cell Chemical Lysis on Microfluidic Chips with Arrays of Microwells
by: Nikolay A. Maslov, et al.
Published: (2011-12-01) -
High-density microwell chip for culture and analysis of stem cells.
by: Sara Lindström, et al.
Published: (2009-09-01) -
Automated dielectrophoresis with microwell chips
by: Broche, Lionel Marc
Published: (2009) -
Facile Method for Fabricating Microfluidic Chip Integrated with Microwell Arrays for Cell Trapping
by: Hongyue Wu, et al.
Published: (2019-10-01) -
Single-Cell Electric Lysis on an Electroosmotic-Driven Microfluidic Chip with Arrays of Microwells
by: Yu-Hung Chen, et al.
Published: (2012-05-01)